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Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • New Research Shows Drugs Associated with a Risk of Depression Are Widely Used [hide all summaries]
    (October 2018)
    In this article, we summarize the results of a recent research study showing that use of medications that have depression as a potential adverse effect is very common. We also identify some of the many prescription medications that can cause depression symptoms, including suicidal thoughts or behavior.
  • Review of Gabapentin [hide all summaries]
    (March 2018)
    The FDA has approved gabapentin (NEURONTIN) for several conditions, including a type of seizure disorder, shingles pain and restless leg syndrome. Hear our recommendations for who should use gabapentin and who should avoid it.
  • Drug-Induced Movement Disorders [hide all summaries]
    (February 2018)
    Abnormal involuntary movements (movement disorders) occur as adverse events associated with many widely used medications and can cause substantial hardship for affected individuals. Find out which drugs are associated with these adverse effects.
  • Drugs That Cause Weight Gain [hide all summaries]
    (December 2017)
    Weight gain is an adverse event associated with many widely used medications and may lead to significant overweight and obesity, especially in susceptible individuals. Find out which drugs have this adverse effect.
  • Important Questions About Shingles [hide all summaries]
    (June 2016)
    Shingles is a very common disease caused by the chicken (herpes zoster) virus. Elderly adults are particularly vulnerable to developing this painful and sometimes debilitating condition. Learn the facts about shingles and how you can lower your risk of developing it.
  • Antacid Drug Interactions [hide all summaries]
    (October 2009)
    Antacids can interact with a number of medications, either increasing or decreasing drug effect.
  • Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia [hide all summaries]
    (April 2009)
    This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
  • New Evidence of Suicidal Thinking and Behavior In Patients Using Anti-Epileptic Drugs [hide all summaries]
    (November 2008)
    Among patients taking antiepileptic drugs for epilepsy, the risk of suicidal thinking and behavior was 3.5 times greater compared to placebo. These drugs are also used to treat pain and as mood stabilizers in people with manic-depressive disorders. Pay attention to common warning signs that may indicate an increased risk of suicide, including: talking or thinking about hurting oneself or ending one’s life; withdrawal from family and friends; worsening depression; increased preoccupation with death and dying; giving away prized possessions. Do not make any medication regimen changes without consulting your provider. Unsupervised sudden changes in prescription drugs can have dangerous adverse effects
  • The Danger of Prescribing without Proof: Examples of Prescriptions for Drugs Not Shown to be Safe and Effective [hide all summaries]
    (July 2006)
    The article discusses numerous recent examples of the harm that has been caused by off-label prescribing, including the heart drugs amiodarone (Cordarone), many antipsychotic drugs, topiramate (Topamax)and several antidepressants.
  • Off-label Prescribing: Prescribing without Proof Can Lead to Harm [hide all summaries]
    (July 2006)
    21 percent of the prescriptions written in 2001 in the United States were for drugs that were not deemed to be safe and effective to treat the diseases or symptoms for which they were prescribed. If you have been prescribed a drug for an off-label (unapproved) use, ask your physician about the science supporting the use of the drug and ask if a drug that is approved for that use could be substituted.
  • Update on the Illegal Promotion of Gabapentin (NEURONTIN) [hide all summaries]
    (September 2002)
    Court documents revealed that senior officials at Parke-Davis determined that it was not sufficiently profitable for Parke-Davis to obtain FDA approval for gabapentin’s alternative uses mentioned above by doing the types of studies necessary for approval. Instead, company officials developed a strategy that would allow Parke-Davis to avoid the costs of proving gabapentin’s safety and effectiveness for these other uses, while allowing the company to enter the lucrative off-label markets.
  • Neurontin (GABAPENTIN) - The Illegal Corporate Creation of a Blockbuster Drug [hide all summaries]
    (May 2002)
    A March 14, 2002, New York Times article revealed that the manufacturer of the seizure medication gabapentin (NEURONTIN) illegally promoted the drug to prescribing physicians for at least 11 “off-label” (unapproved) medical conditions, using their own employees, euphemistically called “medical liaisons.” Many of the bases for the safety and effectiveness of gabapentin for these 11 unapproved uses appears to have been fabrications by the corporation.
  • Review of Anti-Seizure Drugs For Bipolar Disorder [hide all summaries]
    (March 2001)
    The editors of the highly respected Medical Letter on Drugs and Therapeutics, for doctors and pharmacists, reviewed evidence from controlled clinical trials of anti-seizure drugs for psychiatric disorders in the December 11, 2000 issue. Controlled clinical trials are the “gold standard” for testing the effectiveness of drugs.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion

Health Letter Articles

Search results below include Health Letter Articles where your selected drug is a primary subject of discussion

SHOW secondary search results for gabapentin (GRALISE, NEURONTIN)

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