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These are examples of drugs Worst Pills warned readers about well before they were taken off the market. We warned readers not to use seven of these 11 drugs more than two years before they were banned — in one case, Darvon, 22 years before it was banned.
| Generic Name (Brand Name) | Date Withdrawn in US | Worst Pills, Best Pills Readers Warned DO NOT USE |
| Rofecoxib (VIOXX) | September 2004 | April 2001 |
| Nefazadone (SERZONE)* | May 2004 | February 2002 |
| Cerivastatin (BAYCOL) | August 2001 | March 1998 |
| Alosetron (LOTRONEX)** | November 2000 | August 2000 |
| Cisapride (PROPULSID) | March 2000 | August 1998 |
| Troglitazone (REZULIN) | March 2000 | January 1998 |
| Grepafloxacin (RAXAR) | October 1999 | April 1998 |
| Bromfenac (DURACT) | June 1998 | December 1997 |
| Dexfenfluramine (REDUX) | September 1997 | July 1996 |
| Sibutramine (MERIDIA) | October 2010 | March 1998 |
| Propoxyphene (DARVON) | November 2010 | May 1988 |
*After HRG petition and lawsuit, Bristol-Myers Squibb withdrew drug as did most generic manufacturers; some generic manufacturers still sell it
**Taken off the market then reintroduced under very tight restrictions: little use
