Worst Pills
conjugated estrogens (PREMARIN)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • Hormone Replacement Therapy [hide all summaries]
    In 1991, the Health Research Group published the Women’s Health Alert. The largest chapter in the book was on hormone replacement therapy (HRT). By then, the evidence was clear that these drugs caused breast cancer, and very serious doubts had been raised about their ability to protect against heart disease. The first sentence in this chapter began: Female replacement hormones may someday be remembered as the most recklessly prescribed and dangerous drugs of this century.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Medications That Induce Breast Enlargement in Men [hide all summaries]
    (May 2019)
    For men, abnormally large breasts can be distressing and embarrassing. Find out about the numerous drugs that can cause breast enlargement in men.
  • USPSTF Recommends Against Hormone Therapy to Prevent Chronic Conditions in Postmenopausal Women [hide all summaries]
    (May 2018)
    This article reviews the recent recommendation issued by the U.S. Preventive Services Task Force, an independent volunteer panel of national experts in disease prevention, against the use of hormone replacement therapy in postmenopausal women in order to prevent chronic conditions such as heart disease, stroke, diabetes, dementia, cancer and osteoporosis.
  • Nonsurgical Treatments for Urinary Incontinence [hide all summaries]
    (May 2017)
    Urinary incontinence — the inability to control the passage of urine — is a widespread problem that affects an estimated 25 million American adults. Learn about lifestyle changes and non-drug therapies that should be the first-choice treatments for incontinence, as well as the best drugs to use as second-choice treatment options.
  • Drugs That Cause Sun-Related Skin Reactions [hide all summaries]
    (July 2016)
    Summer is a terrific time for healthy outdoor activities, such as walking, hiking, biking and swim¬ming. But for an unlucky few, certain medications can lead to adverse skin reactions following exposure to the sun. Find out whether you are at risk and how to protect yourself.
  • Drugs That Cause Loss of Bladder Control [hide all summaries]
    (February 2016)
    Urinary incontinence, or loss of bladder control, is a common and often embarrassing problem that can have a huge impact on quality of life. Find out which drugs can cause this problem.
  • More Evidence Linking Hormone Therapy To Cardiovascular Harm in Postmenopausal Women [hide all summaries]
    (October 2015)
    In this article, we discuss the most recent evidence linking the use of hormone replacement therapy in women after menopause to increased risk of heart attacks, strokes and other serious cardiovascular problems.
  • Hormone Replacement Therapy: Use at the Lowest Dose for the Shortest Amount of Time [hide all summaries]
    (January 2014)
    The dangers of hormone replacement therapy (HRT) are in direct proportion to the length of time for which they are used. This article discusses strategies for keeping dosage and exposure to a minimum and recommends only using HRT for debilitating hot flash symptoms. Nondrug remedies for milder symptoms also are discussed.
  • Quality of Drug Prescribing [hide all summaries]
    (March 2011)
    The article reviews a study on the potentially dangerous, inappropriate prescribing of 77 drugs that pose a high risk to older adults. Of the 67 of these drugs that we had previously reviewed in Worst, Pills, Best Pills News, we had classified 60 (90 percent) of them as “Do Not Use,” and the other seven as "Limited Use."
  • Beware: Bioidentical Hormones [hide all summaries]
    (September 2010)
    Many women are using so-called bioidentical hormones, "natural" and implicitly safer versions of prescription drugs such as Premarin, because the latter drugs have been found to cause breast cancer, heart disease and many other serious health problems. The article discusses the fact that these products can be expected to have the same serious adverse effects that con­ventional preparations have and that they have the added disadvantage of not being regulated and thereby having unpredictable amounts of ingredients.
  • A Review of Bioidentical Hormone Replacement Therapy (BHRT) Manufactured by Compounding Pharmacists [hide all summaries]
    (August 2006)
    Two industries peddling hormone replacement drugs became involved in a conflict with one another on October 6, 2005, when the pharmaceutical company Wyeth filed a petition with the FDA urging the agency to counter flagrant violations of the law by pharmacies compounding Bioidentical Hormone Replacement Therapy Drugs. Both sides have been very culpable in assaults on women's health.
  • The Danger of Prescribing without Proof: Examples of Prescriptions for Drugs Not Shown to be Safe and Effective [hide all summaries]
    (July 2006)
    The article discusses numerous recent examples of the harm that has been caused by off-label prescribing, including the heart drugs amiodarone (Cordarone), many antipsychotic drugs, topiramate (Topamax)and several antidepressants.
  • Postmenopausal Hormone Replacement Therapy (HRT) and Urinary Incontinence [hide all summaries]
    (January 2006)
    If you are considering starting HRT (hormone replacement therapy), the possibility of experiencing urinary incontinence should be taken into account along with its other potential harms, which are outlined in the black box warning accompanying this article.
  • Drug Induced Psychiatric Symptoms [hide all summaries]
    (October 2002)
    This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.
  • Long Term Hormone Replacement Therapy (HRT): The Demise of a Standard of Practice [hide all summaries]
    (September 2002)
    We hope that by now women have heard that one part of a large, long term, government sponsored clinical trial, the Women’s Health Initiative, evaluating hormone replacement therapy (HRT) was halted prematurely. The bottom line from this trial is that long term HRT’s risks outweigh its benefits. You should not be using hormone replacement therapy for any reason other than its very short term use to control the symptoms of menopause.

Additional Information from Public Citizen

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Health Letter Articles

Search results below include Health Letter Articles where your selected drug is a primary subject of discussion
  • Outrage: We Have Met the Enemy and He is Us [hide all summaries]
    (November 2003)
    FDA’s announcement on September 9 of a “Collaborative Campaign to Inform Women About Menopausal Hormone Therapy” sounded as though it might hold some promise; that is, until you actually went to the Collaborative Campaign web site Instead of the dry, fact-filled explanation of the risks and benefits of HRT one might expect from the FDA, the opening page on the site contained no substantive information whatsoever.

SHOW secondary search results for conjugated estrogens (PREMARIN)

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