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lamotrigine (LAMICTAL)

Worst Pills, Best Pills Newsletter Articles

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  • New Research Shows Drugs Associated with a Risk of Depression Are Widely Used [hide all summaries]
    (October 2018)
    In this article, we summarize the results of a recent research study showing that use of medications that have depression as a potential adverse effect is very common. We also identify some of the many prescription medications that can cause depression symptoms, including suicidal thoughts or behavior.
  • Review of Lamotrigine (LAMICTAL) [hide all summaries]
    (October 2018)
    For certain types of epilepsy, lamotrigine is an appropriate treatment for preventing seizures. Learn about the common and serious adverse effects that can occur while taking this drug and how to take this drug safely.
  • Drug-Induced Movement Disorders [hide all summaries]
    (February 2018)
    Abnormal involuntary movements (movement disorders) occur as adverse events associated with many widely used medications and can cause substantial hardship for affected individuals. Find out which drugs are associated with these adverse effects.
  • Medications for Bipolar Disorder [hide all summaries]
    (March 2017)
    Bipolar disorder, also known as manic depression, is a serious chronic mental illness that afflicts approximately 5.4 million people in the U.S. In this article, we review the benefits and safety of several drugs that are commonly used to treat this disorder.
  • Lamotrigine (LAMICTAL): Risk of Aseptic Meningitis [hide all summaries]
    (November 2010)
    Non-bacterial (aseptic) meningitis has been found in some people using the anti-convulsant drug lamotrigine (LAMICTAL), which is also used to treat bipolar illness. This article explains the symptoms of meningitis, what to do if these symptoms occur and how to prevent drug-induced meningitis.
  • Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia [hide all summaries]
    (April 2009)
    This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
  • New Evidence of Suicidal Thinking and Behavior In Patients Using Anti-Epileptic Drugs [hide all summaries]
    (November 2008)
    Among patients taking antiepileptic drugs for epilepsy, the risk of suicidal thinking and behavior was 3.5 times greater compared to placebo. These drugs are also used to treat pain and as mood stabilizers in people with manic-depressive disorders. Pay attention to common warning signs that may indicate an increased risk of suicide, including: talking or thinking about hurting oneself or ending one’s life; withdrawal from family and friends; worsening depression; increased preoccupation with death and dying; giving away prized possessions. Do not make any medication regimen changes without consulting your provider. Unsupervised sudden changes in prescription drugs can have dangerous adverse effects
  • Tizanidine: Watch Out for Drugs Interacting With This Muscle Relaxant [hide all summaries]
    (October 2008)
    Tizanidine (ZANAFLEX) is a muscle relaxant for which more than 3.8 million prescriptions were filled in the U.S. last year. The article lists more than 64 drugs with which it can have dangerous interactions resulting in excess sedation, difficulty breathing or dangerously low blood pressure that can result in falling.
  • Using Seizure and Depression Drug Lamotrigine (LAMICTAL) While Pregnant May Result in Birth Defects [hide all summaries]
    (January 2007)
    The seizure and depression drug lamotrigine (LAMICTAL) may cause birth defects when taken during the first trimester of pregnancy. Specifically, the drug may cause either or both cleft lip (a gap in the upper lip) and cleft palate (a gap the roof of the mouth) in babies. If you are taking lamotrigine and become pregnant, consult the prescribing physician immediately. DO NOT discontinue any seizure medication without first consulting the prescriber.
  • Seizure Medication Lamotrigine (LAMICTAL) Approved For Use In Bipolar Disorder [hide all summaries]
    (August 2003)
    GlaxoSmithKline of Research Triangle Park, NC announced in June 2003 that their seizure medication lamotrigine (LAMICTAL) had been approved by the Food and Drug Administration (FDA) for the maintenance treatment of bipolar I disorder to delay the time to occurrence of mood episodes such as depression, mania (periods of severe highs), hypomania, or mixed episodes in patients also being treated with standard therapy. If you make the decision to use lamotrigine for bipolar I disorder and if a rash appears, report it to your physician immediately and the drug should be discontinued.
  • Important Drug Warning! Dispensing Errors Continue With Lamotrigine (LAMICTAL) [hide all summaries]
    (February 2002)
    In the August 2000 issue of Worst Pills, Best Pills News we wrote about reports of dispensing errors involving the drugs lamotrigine (LAMICTAL) and terbinafine (LAMISIL). Lamotrigine is approved by the Food and Drug Administration (FDA) for certain types of seizure disorders and terbinafine for the treatment of toenail and fingernail fungal infections.
  • Review of Anti-Seizure Drugs For Bipolar Disorder [hide all summaries]
    (March 2001)
    The editors of the highly respected Medical Letter on Drugs and Therapeutics, for doctors and pharmacists, reviewed evidence from controlled clinical trials of anti-seizure drugs for psychiatric disorders in the December 11, 2000 issue. Controlled clinical trials are the “gold standard” for testing the effectiveness of drugs.

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