Worst Pills
methylprednisolone (MEDROL)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
Search results below include drug profiles where your selected drug is a primary subject of discussion

Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • Adrenal Steroids [hide all summaries]
    There are three types of adrenal steroids: mineralocorticoids, which maintain sodium and potassium balance in the body, glucocorticoids, and male sex steroids (although most male sex hormones are produced in the testicles). Our Web site only considers glucocorticoids.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Owner, Lead Compounding Pharmacist of Drugmaker Linked to Meningitis Outbreak Charged With Murder [hide all summaries]
    (April 2015)
    In December 2014, a federal grand jury in Boston indicted 14 executives and employees of a Massachusetts compounding phar¬macy on 131 criminal charges in connec¬tion with a deadly nationwide fungal meningitis outbreak. Learn the shocking details of how the company put the lives of thousands of patients around the country at risk.
  • Do Not Use Steroid Injections for Back Pain [hide all summaries]
    (July 2014)
    Steroid injections are very commonly used to treat back pain. Find out why Public Citizen’s Health Research Group now recommends against such treatment.
  • Fungal Meningitis Outbreak Highlights the Dangers of Compounding Pharmacies [hide all summaries]
    (December 2012)
    Public Citizen has a long history of opposing the dangerous under-regulation of large-scale pharmacy compounders such as the New England Compounding Center, which is at the center of the recent outbreak of fungal meningitis caused by contaminated injectable steroids. Learn how this current nationwide disaster, and its related deaths, could have been prevented.
  • Update on Grapefruit Juice-Drug Interactions [hide all summaries]
    (July 2012)
    This article updates and expands our earlier list of drugs that can have harmful interactions with grapefruit juice. The list now includes 82 different drugs.
  • Corticosteroid Drug Interactions [hide all summaries]
    (November 2010)
    This article discusses 36 drugs that, when used by people also using a corticosteroid, can either cause toxic interactions with the steroid or decrease the steroid's effectiveness.
  • Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia [hide all summaries]
    (April 2009)
    This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
  • Drug-Induced Eye Toxicity: 62 Drugs That Can Cause Eye Disease [hide all summaries]
    (April 2008)
    This article, based on a recent review in Drug Safety, lists 62 prescription drugs that can cause eye disease. The range of drug-induced eye diseases includes diseases of the eyelids, glaucoma, cataracts, retinal damage and optic nerve damage. As is true for drug-induced diseases in other parts of the body, you should consider newly developed eye symptoms beginning shortly after starting a new medication to be possibly drug-induced and consult a physician.
  • Grapefruit Juice and Prescription Drugs: Some Dangerous Interactions [hide all summaries]
    (February 2004)
    The January 5th issue of the Medical Letter, a widely respected source of independent information about pharmaceuticals and dietary supplements, has a review of the increasingly researched problem of the interaction between grapefruit juice and many prescription and over-the-counter drugs. Like most interactions between chemicals in the body, this one involves the impairment, by grapefruit juice, of the body’s ability to metabolize many drugs, leading to higher than expected — and sometimes dangerous — levels of these drugs.This article lists the drugs.
  • Grapefruit Juice and Drug Interactions [hide all summaries]
    (June 2002)
    Grapefruit juice can interact with a number of therapeutically important drugs that could lead to the possibility of toxicity. These drugs are listed in the article.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • Petition Requesting Warnings on the Labels of Glucocorticosteroids (HRG Publication #1958) [hide all summaries]
    The FDA should immediately require that the labels for all brands of prednisone and other glucocorticosteroids currently on the market in the U.S. be revised to include central serous chorioretinopathy as one of the ophthalmic adverse reactions reported with these medications if not already included. The FDA should also ensure that other important information regarding the use and safety of these medications is presented in a consistent manner across all labels.

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