Worst Pills
amlodipine (NORVASC)

Drug and Dietary Supplement Profiles

A comprehensive review of the safety and effectiveness of this drug. If the drug is not a Do Not Use product, information on adverse effects, drug interactions and how to use the medication are included.
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Disease and Drug Family Information

Search results below include Disease and Drug Family Information where your selected drug is a primary subject of discussion
  • High Blood Pressure [hide all summaries]
    A study of nutritional therapy showed that over one-third of people who previously needed drug treatment for high blood pressure were able to adequately control their blood pressure with nutritional therapy alone.Several factors should be taken into account when considering whether your high blood pressure should be treated. One is the benefits of the treatment for your blood pressure, which vary significantly depending on how high it is, your age, and whether you have other risk factors such as high cholesterol or are a smoker or a diabetic, and whether you have had a heart attack, heart failure, a stroke, or have kidney damage. The other consideration is the risks or the adverse effects of the treatment, which will vary depending on what is being considered.

Worst Pills, Best Pills Newsletter Articles

Search results below include Worst Pills, Best Pills Newsletter Articles where your selected drug is a primary subject of discussion
  • Update on Grapefruit Juice-Drug Interactions [hide all summaries]
    (July 2012)
    This article updates and expands our earlier list of drugs that can have harmful interactions with grapefruit juice. The list now includes 82 different drugs.
  • Some Anti-Hypertensive Drugs Increase the Risk of Gout [hide all summaries]
    (May 2012)
    The article lists many drugs that treat high blood pressure but can also increase the risk of gout. If you have gout, ask your doctor whether your dose of any of these drugs could be reduced or whether you should switch to a medication with a lower gout risk. However, hypertension control is of utmost importance.
  • Drug-Induced Parkinsonism [hide all summaries]
    (October 2010)
    A study discovered that more than 1 out of every 10 people who went to a Parkinson’s disease center was found to have drug-induced Parkinsonism. These people were misdiagnosed as having the more common illness, Parkinson’s disease, which is irreversible and has unknown causes.
  • Calcium Channel Blocker Drug Interactions [hide all summaries]
    (May 2008)
    This article lists more than 60 prescription drugs that can interact with calcium channel blocking drugs such as amlodipine (NORVASC),diltiazem (CARDIZEM, DILACOR XR TIAZAC)or nifedipine (PROCARDIA)to either cause toxicity or to lessen the effectiveness of the calcium channel blocking drugs. Included in the lists are a number of drugs that we list in Worst Pills, Best Pills as DO NOT USE or LIMITED USE drugs. The article also explains the different kinds of toxicity that can ensue from these interactions.
  • Drug-Induced Taste Disorders [hide all summaries]
    (September 2003)
    DO NOT stop taking any of the drugs listed in the table without first consulting your physician. You should report any alteration in your sense of taste to your physician if you are taking a drug.
  • Drug Induced Psychiatric Symptoms [hide all summaries]
    (October 2002)
    This is the first of a two part series on drug induced psychiatric symptoms that is based on the July 8, 2002 issue of The Medical Letter on Drugs and Therapeutics. Regular readers of Worst Pills, Best Pills News will recognize The Medical Letter as a reference source written for physicians and pharmacists that we often use because of its reputation as an objective and independent source of drug information. The article lists the drugs and their psychiatric adverse effects.
  • Grapefruit Juice and Drug Interactions [hide all summaries]
    (June 2002)
    Grapefruit juice can interact with a number of therapeutically important drugs that could lead to the possibility of toxicity. These drugs are listed in the article.
  • Older Adults Not Getting the Most Effective Drugs For High Blood Pressure [hide all summaries]
    (January 2001)
    “You, or at least many of your colleagues, have failed to provide optimal care to your patients with high blood pressure.” This stinging critique of physician prescribing practices starts off an editorial in the Journal of General Internal Medicine for October 2000 that commented on a Harvard Medical School study of high blood pressure in older adults that appeared in the same issue.

Additional Information from Public Citizen

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