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bedaquiline (SIRTURO)

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  • Troubling New Drug Approvals in 2012 [hide all summaries]
    (March 2013)
    Find out which drugs approved in 2012 have risks greatly exceeding their benefits or no meaningful benefits. If you are using any of the DO NOT USE drugs reviewed in the article, talk to your doctor before stopping their use.
  • Harming Tuberculosis Patients Instead of Helping Them? [hide all summaries]
    (February 2013)
    Although there are not many cases in the United States, multiple drug-resistant tuberculosis (MDR TB) is a serious international problem. In a trial for a new drug for MDR TB, bedaquiline (SIRTURO), those receiving the drug were five times more likely to die than those receiving a placebo. Instead of looking into this more carefully, the Food and Drug Administration (FDA) approved the drug with the warning: “In one clinical trial, more deaths were seen in people who were treated with SIRTURO compared to people who did not receive SIRTURO.”

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