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Worst Pills, Best Pills Newsletter Articles

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  • Alternatives for Sleeping Problems [hide all summaries]
    (July 2010)
    Experts in sleep and aging have stated, “It’s extraordinarily rare to find an old person who actually requires sleeping pills." This article lists many over-the-counter and prescription drugs that can actually cause difficulty with sleeping and also discusses a variety of non-pharmacologic alternatives to sleeping pills. Sleep experts have also said that “Nonpharmacological treat­ments not only cause fewer side ef­fects, but they can sustain long-term improvements more successfully than pharmacological treatments.”
  • Drug-induced Cognitive Impairment: Part 2: Delirium and Dementia [hide all summaries]
    (April 2009)
    This second article about drug-induced dementia or delirium lists and discusses an additional 79 drugs that can cause these reversible kinds of mental deterioration. The two articles collectively review 136 drugs that can cause these serious side effects, especially in older people.
  • Colchicine Interactions with Other Drugs Can Be Life-Threatening [hide all summaries]
    (December 2008)
    This article lists 27 drugs that can have life-threatening interactions with the widely-used gout drug, colchicine, resulting in dangerously elevated levels of colchicine. Too much colchicine in the body leads to toxicity such as fever, vomiting, diarrhea, abdominal pain and muscle pains. Even worse, it can impair the bone marrow’s ability to make red and white blood cells, causing severe anemia and dangerously low numbers of white blood cells. When the number of white blood cells is reduced, your body may have difficulty fighting infections. Most people who have died from colchicine toxicity have had bone marrow toxicity or had preexisting kidney problems. Every patient on colchicine — whether on other drugs or not — should be alert for evidence of colchicine toxicity as described above.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • Petition Requesting Warnings on the Labels of Glucocorticosteroids (HRG Publication #1958) [hide all summaries]
    The FDA should immediately require that the labels for all brands of prednisone and other glucocorticosteroids currently on the market in the U.S. be revised to include central serous chorioretinopathy as one of the ophthalmic adverse reactions reported with these medications if not already included. The FDA should also ensure that other important information regarding the use and safety of these medications is presented in a consistent manner across all labels.

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