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ibandronate (BONIVA)

Worst Pills, Best Pills Newsletter Articles

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  • Questions & Answers [hide all summaries]
    (May 2016)
    In this month’s Question & Answer feature, we respond to a reader’s request to explain why we recommend use of bisphosphonates for certain patients with osteoporosis despite our warnings about their risks.
  • A Guide to Treatments for Osteoporosis [hide all summaries]
    (May 2015)
    Drug treatment can prevent broken bones in some women with osteoporosis. But drugs are not always necessary and can cause harmful side effects, especially when treatment lasts longer than needed. Read this article to learn who should take osteoporosis drugs, which drugs to take and for how long.
  • Preserving Bones with Bisphosphonates: Should You Avoid NSAIDs? [hide all summaries]
    (July 2010)
    It appears likely that patients who take bisphosphonates (such as FOSAMAX) and NSAIDs at the same time have an increased risk of gastrointestinal ulcers as opposed to taking either drug alone. The article reviews the studies demonstrating this and offers some practical advice on what the cautious drug user should do.
  • Long-term Use of Bisphosphonates for Osteoporosis [hide all summaries]
    (January 2009)
    Emerging reports of a rare but unique type of fracture in patients receiving bisphosphonates for many years point toward the drug as a possible culprit. Unlike most drugs, bisphosphonates remain in your body for many years after you stop taking them. Further investigation into the risks, as well as benefits, of long-term bisphosphonate use is needed. But, because there is little evidence of benefit after five years and the long-term risks remain largely unknown, it is reasonable to discuss with your doctor discontinuing these drugs after five years. However, you should continue to take calcium and vitamin D supplements at currently suggested doses (discussed in the article) regardless of whether or not you are on bisphosphonates.
  • Osteoporosis Fracture Prevention: What You Need to Know about Drugs and other Measures - Part 2 [hide all summaries]
    (December 2008)
    The article discusses the difference between the benefits of drugs to prevent a first fracture (primary prevention) and to prevent further fractures in people who have already experienced a fracture (secondary prevention). In addition to discussing when it may or may not be appropriate to use drugs such as Fosamax (alendronate) or Actonel (risedronate) the article discusses ways of preventing falls and other non-pharmacologic approaches to preventing fractures.
  • A Review of Ibandronate (BONIVA) For Osteoporosis [hide all summaries]
    (October 2006)
    Although this osteoporosis drug has been shown to decrease vertebral fractures, which involve the bones that make up the spine, the drug did not show any decrease in nonvertebral fractures, such as hip fractures, in postmenopausal women. We know more about the older, alternative drugs for osteoporosis.
  • Death of Parts of the Jaw Bone With Osteoporosis Drugs Such As Alendronate (FOSAMAX) [hide all summaries]
    (September 2006)
    The typical signs and symptoms of osteonecrosis of the jaw may include pain, swelling or infection of the gums, loosening of the teeth, poor healing of the gums, numbness or a feeling of heaviness in the jaw, drainage and exposed bone. Patients taking a bisphosphonate (including Fosamax) should carefully monitor themselves for any sign of jaw problems resembling those described in this article.

Additional Information from Public Citizen

Search results below include Additional Information from Public Citizen where your selected drug is a primary subject of discussion
  • Testimony Regarding Bisphosphonates (HRG Publication #1970) [hide all summaries]
    Long-term use of bisphosphonates for the prevention of osteoporotic fractures must be limited to 5 years, and the indication for bisphosphonate treatment for osteopenic women must be removed, unless the patient has a significant 10-year fracture risk as determined by the World Health Organization’s (WHO) FRAX algorithm.

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