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Worst Pills, Best Pills Newsletter Articles

  View the entire January 2018 issue in PDF format

  • Do Not Use Olmesartan for High Blood Pressure
    (January 2018)
    Olmesartan (BENICAR) is one of eight drugs in the family of commonly used blood pressure-lowering medications known as angiotensin II receptor blockers. Learn about the severe, life-threatening gastrointestinal adverse effects of olmesartan that could land you in the hospital.
  • Opioid Maker Executives “No Better Than Street-Level Drug Dealers”
    (January 2018)
    Worst Pills, Best Pills News Editor Dr. Michael Carome discusses the recent arrest of John Kapoor, the billionaire founder of Insys Therapeutics — the drug company that markets fentanyl sublingual spray (SUBSYS), a highly addictive, dangerous opioid drug. Kapoor has been charged with “leading a nationwide conspiracy” to profit by bribing doctors to inappropriately prescribe the company’s fentanyl spray product.
  • Study Links Sleeping Pills to Hip Fractures in the Elderly
    (January 2018)
    Every year, more than 300,000 older Americans are hospitalized due to hip fractures, and almost all of these fractures are caused by falls. Read about new research further linking use of sleeping pills to an increased risk of falls and serious injury.
  • Milnacipran For Fibromyalgia: Do Not Use
    (January 2018)
    Milnacipran (SAVELLA) was approved by the Food and Drug Administration in 2009 for the treatment of fibromyalgia in adults, which remains its only approved use. In this article, we review data showing that the drug is ineffective for treating fibromyalgia and dangerous.
  • Do Not Use Mirabegron (MYRBETRIQ) for Overactive Bladder
    (January 2018)
    Overactive bladder is a bothersome — but not serious — medical problem that becomes more common with age. Find out why mirabegron is the wrong choice for treating this condition.

  View the entire December 2017 issue in PDF format

  • The Dangerous Diabetes Drug Pramlintide: Do Not Use
    (December 2017)
    In this article, we explain why the serious adverse effects of the injected diabetes drug pramlintide far outweigh the drug’s limited benefits.
  • At the Behest of the Opioid Drug Industry, Congress Undermined the DEA
    (December 2017)
    Worst Pills, Best Pills News Editor Dr. Michael Carome discusses how the opioid drug industry successfully lobbied Congress to pass a dangerous bill that effectively stripped the Drug Enforcement Agency of one of its strongest enforcement tools for fighting the illegal diversion of opioid drugs.
  • Drugs That Cause Weight Gain
    (December 2017)
    Weight gain is an adverse event associated with many widely used medications and may lead to significant overweight and obesity, especially in susceptible individuals. Find out which drugs have this adverse effect.
  • Drug for Treating Nighttime Urination Too Dangerous
    (December 2017)
    Nighttime urination is a common symptom that becomes more common with increasing age. Learn why the only drug approved for treating this symptom offers only meager benefits along with unacceptable risks.
  • Rifaximin (XIFAXAN): Another Poor Choice for Treating Irritable Bowel Syndrome
    (December 2017)
    Rifaximin was approved by the FDA in May 2015 for treating irritable bowel syndrome with diarrhea as the predominant symptom in adults. Find out about the drug’s serious adverse effects that outweigh its limited benefits.

  View the entire November 2017 issue in PDF format

  • Do Not Use the New Blood Thinner Edoxaban (SAVAYSA)
    (November 2017)
    Learn why edoxaban, one of the new blood thinners approved by the FDA, is not the best option for preventing dangerous blood clots in patients with atrial fibrillation.
  • FDA Cracks Down on Illegal Stem Cell Treatments
    (November 2017)
    Over the past decade, the number of clinics in the U.S. that peddle unproven stem cell "treatments" directly to consumers exploded from a handful in 2010 to as many as 570 in 2016. Find out what the FDA is finally doing to clamp down on the marketing of illegal stem cell treatments.
  • Corticosteroid Injections Not Beneficial for Knee Osteoarthritis
    (November 2017)
    The injection of corticosteroids into the knee joints of patients with osteoarthritis of the knee is a widespread practice. Find out the results of new research funded by the National Institutes of Health showing that such injections actually may accelerate joint damage.
  • Subclinical Hypothyroidism: When to Treat
    (November 2017)
    In this article, we describe a common condition known as subclinical hypothyroidism and discuss which patients with this condition should be treated with thyroid hormone replacement.
  • News Brief for November 2017
    (November 2017)
    In this month’s news brief, we report the FDA’s reckless decision to deny Public Citizen’s petition to ban a dangerous anti-fungal drug.
  • Pregabalin (LYRICA): Neither Effective nor Safe for Treating Sciatica Leg Pain
    (November 2017)
    Doctors often prescribe pregabalin for a neuropathic pain condition known as sciatica, a use that is not approved by FDA. Find out why pregabalin is a bad choice for treating sciatica.
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